What to Expect from Grey’s Anatomy Season 22 Episode 4: Goodbye Horses
Jackson Avery returns, but with bad news for Meredith, on Grey’s Anatomy Season 22 Episode 4, “Goodbye Horses.”
While Meredith has been spending her time at Grey-Sloan, things have apparently been moving forward elsewhere. She finds out that Jackson let Tom Koracick publish his Alzheimer’s results, despite the fact that his research had only been on male mice.
Meanwhile, Link is discharged from the hospital, and the relationship between Teddy and Cass Beckman makes for an awkward encounter with Owen.
Here’s everything you need to know about this episode, including the air date, cast, promo, and how to watch.
Grey’s Anatomy Season 22 Episode 4 Details
- Title: “Goodbye Horses”
- Air Date: Thursday, October 30th, 2025
- Time: 10/9c
- Network: ABC
How to Watch Grey’s Anatomy Season 22 Episode 4
- Live: ABC at 10/9c
- Streaming: Available next day on Hulu
Grey’s Anatomy Season 22 Episode 4 Description
The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.
Guest Stars & Returning Characters
- Cast: Chandra Wilson, Kevin McKidd, Kim Raver, James Pickens Jr., Chris Carmack, Camilla Luddington, Anthony Hill, Jason George, Alexis Floyd, Adelaide Kaine, Harry Shum Jr., Nico Terho, Trevor Jackson, Ellen Pompeo
- Guest Stars: Jesse Williams, Sophia Bush, Floriana Lima, Samantha Marie Ware, Raphael Alejandro, Manny Magnus, Anton Starkman
- Notable Returns: Jesse Williams as Jackson Avery, Sophia Bush as Cass Beckman, Floriana Lima as Nora Young
More Photos from Grey’s Anatomy Season 22 Episode 4:
ADELAIDE KANE, KEVIN MCKIDD, RAPHAEL ALEJANDRO, ALEXIS FLOYD, MANNY MAGNUS
SAMANTHA MARIE WARE, CHANDRA WILSON
Promo Video:
What are your hopes for this episode of Grey’s Anatomy? Share your thoughts with us in the comments below, and be sure to catch up with our review of Grey’s Anatomy Season 22 Episode 3 here.
Grey’s Anatomy airs Thursdays at 10/9c on ABC.
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Ashley Bissette Sumerel
Ashley Bissette Sumerel is a television and film critic living in Wilmington, North Carolina. She is editor-in-chief of Tell-Tale TV as well as Eulalie Magazine. Ashley has also written for outlets such as Rolling Stone, Paste Magazine, and Insider. Ashley has been a member of the Critics Choice Association since 2017 and is a Rotten Tomatoes-approved critic. In addition to her work as an editor and critic, Ashley teaches Entertainment Journalism, Composition, and Literature at the University of North Carolina Wilmington.