Watson Season 2 Episode 10, "Never Been CRISPR'd" - (l-r) Ritchie Coster as Shinwell Johnson and Morris Chestnut as Dr. John Watson Watson Season 2 Episode 10 Review: Never Been CRISPR’d

Watson Season 2 Episode 10 Review: Never Been CRISPR’d

Reviews, Watson

It’s a weird enough case for a midseason finale on Watson Season 2 Episode 10 “Never Been CRISPR’d.” But the real drama lurks in almost everyone’s personal lives.

Hobie (of season 1’s glowing chest) hits it off with his new girlfriend, Wendy, but a “love mod” almost kills her on their first real date. Yet when she gets even sicker, Watson attributes it to modification she previously made to herself.

A transfusion will save her, but due to various complications, she’s now essentially allergic to Hobie and his chest. In the end, he reverses the mutation (at great personal risk) to be with her, and leaves John with some poignant words about love.

Watson Season 2 Episode 10, "Never Been CRISPR Watson Season 2 Episode 10 Review: Never Been CRISPR’d'd" - (l-r) Rachel Hayward and Morris Chestnut as Dr. John Watson
“Never Been CRISPR’d” – Pictured (L-R): Rachel Hayward and Morris Chestnut as Dr. John Watson Photo: Colin Bentley/CBS ©2025 CBS Broadcasting, Inc. All Rights Reserved.

Everyone could use a little advice, whether it’s Ingrid, at Adam’s urging, trying to break it off with Beck or Sasha learning of her “uncle’s” death but finding contact info he left her behind that leads to emails between her and her birth mother.

But there are twists, of course. First, we see that Sasha’s emails are actually being sent by Beck. And then John goes to tell Leila he loves her. Except he’s actually going to say it to Mary. Except when he does, he finds her kissing another man.

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On top of everything else, Sherlock returns with his own host of troubling symptoms that could be caused by a brain tumor. Ingrid is prepared to see him and Watson tells Shinwell he’s alive. But he disappears again before anything can progress.

Watson Season 2 Episode 10, "Never Been CRISPR Watson Season 2 Episode 10 Review: Never Been CRISPR’d'd" - (l-r) Robert Carlyle as Sherlock Holmes and Morris Chestnut as Dr. John Watson
“Never Been CRISPR’d” – Pictured (L-R): Robert Carlyle as Sherlock Holmes and Morris Chestnut as Dr. John Watson Photo: Sergei Bachlakov/CBS ©2025 CBS Broadcasting, Inc. All Rights Reserved.

Assuming the technology Hobie and Wendy use is real, the main point of their storyline is probably a cautionary tale of the effects, predictable and not, of messing with elements of genetic makeup. They are very cute, though, and I wish them the best.

I don’t think “the best” is in store for anyone else, at least in the short term. I have my doubts about Ingrid’s pledge to avoid Beck—if nothing else, he’s going to need to be kept around now that he’s focusing his antagonism even more against Sasha.

I’m even more dubious that “Uncle Jun”’s death is as unsuspicious as Lestrade suggests even before we witness him messaging Sasha under the guise of her mother’s emails. If he’s already done the worst, does he have it planned for her next?

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Watson Season 2 Episode 10, "Never Been CRISPR Watson Season 2 Episode 10 Review: Never Been CRISPR’d'd" - (l-r) Eve Harlow as Dr. Ingrid Derian and Morris Chestnut as Dr. John Watson
“Never Been CRISPR’d” – Pictured (L-R): Eve Harlow as Dr. Ingrid Derian and Morris Chestnut as Dr. John Watson Photo: Colin Bentley/CBS ©2025 CBS Broadcasting, Inc. All Rights Reserved.

Comparatively speaking, the pain John runs into at the end of the hour is more ordinary (or at least less life-threatening). Still, I have mixed feelings. As romantic as a rekindling of the Watson marriage could be, Laila at least deserves better.

And then there’s Sherlock. Every time I hope for definitive proof that he’s more that John’s imagining, he’s snatched form the eyes of others. Somewhat ironically, though, the fact he may be dying makes me more confident that he is indeed alive.

In short, we leave our characters for this multi-month break in a place where almost nobody’s immediate future is predictable. Depending on the amount of time that passes in their world, we could return to both loves and lives in peril.


What did you think of this episode of Watson? Share your thoughts in the comments below, and don’t forget to leave your own rating!

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Watson currently airs Mondays at 10/9c on CBS. It will return airing on Sundays on March 1, 2026.

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Caitlin is an elder millennial with an only slightly unhealthy dedication to a random selection of TV shows, from PBS Masterpiece dramas to some of the less popular series on popular networks. Outside of screen time, she's dedicated to the public sector and worthy nonprofits, working to make a difference in the world outside of media.