What to Expect from Grey’s Anatomy Season 22 Episode 2: We Built This City
After the catastrophic events of the season premiere, the doctors at Grey Sloan Memorial begin to move forward on Grey’s Anatomy Season 22 Episode 2, “We Built This City.”
Link works to recover from his injuries, but runs the risk of pushing himself too hard. Meanwhile, Amelia is grieving deeply, and Maggie comes to visit in hopes of helping support her.
Here’s everything you need to know about this episode, including the air date, cast, promo, and how to watch.
Grey’s Anatomy Season 22 Episode 2 Details
- Title: “We Built This City”
- Air Date: Thursday, October 16th, 2025
- Time: 10/9c
- Network: ABC
How to Watch Grey’s Anatomy Season 22 Episode 2
- Live: ABC at 10/9c
- Streaming: Available next day on Hulu
TREVOR JACKSON
Grey’s Anatomy Season 22 Episode 2 Description
The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.
Guest Stars & Returning Characters
- Cast: Chandra Wilson, Kevin McKidd, Kim Raver, Caterina Scorsone, James Pickens Jr., Chris Carmack, Camilla Luddington, Anthony Hill, Jason George, Alexis Floyd, Adelaide Kaine, Harry Shum Jr., Nico Terho, Trevor Jackson, Ellen Pompeo
- Notable Returns: Kelly McCreary as Maggie Pierce
Promo Video:
What are your hopes for this episode of Grey’s Anatomy? Share your thoughts with us in the comments below, and be sure to catch up with our review of Grey’s Anatomy Season 22 Episode 1 here.
Grey’s Anatomy returns Thursday, October 9th on ABC.
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Ashley Bissette Sumerel
Ashley Bissette Sumerel is a television and film critic living in Wilmington, North Carolina. She is editor-in-chief of Tell-Tale TV as well as Eulalie Magazine. Ashley has also written for outlets such as Rolling Stone, Paste Magazine, and Insider. Ashley has been a member of the Critics Choice Association since 2017 and is a Rotten Tomatoes-approved critic. In addition to her work as an editor and critic, Ashley teaches Entertainment Journalism, Composition, and Literature at the University of North Carolina Wilmington.